Entamizole Tablet is a prescription medicine used to treat certain intestinal infections caused by parasites and anaerobic bacteria. It is commonly prescribed for conditions such as amoebiasis (amoebic dysentery) and giardiasis. The medicine combines two active ingredients—metronidazole and diloxanide furoate—which work together to eliminate infection and help relieve symptoms such as diarrhea, abdominal pain, and intestinal discomfort.
Uses of Entamizole Tablet
Doctors may prescribe Entamizole Tablet for:
- Intestinal amoebiasis (amoebic dysentery)
- Asymptomatic intestinal amoeba carriers
- Giardiasis
- Mixed protozoal and anaerobic bacterial intestinal infections
- Certain gastrointestinal infections caused by susceptible organisms
This medicine should only be used when prescribed by a qualified healthcare professional. It is not effective against viral infections.
How Entamizole Tablet Works
Entamizole contains two active ingredients:
- Metronidazole destroys parasites and anaerobic bacteria by damaging their DNA, preventing them from growing and multiplying.
- Diloxanide Furoate acts mainly within the intestine to eliminate amoebae that remain in the bowel after treatment, helping reduce the risk of persistent infection or recurrence.
Together, these ingredients provide both tissue and intestinal activity against amoebic infections.
How to Take Entamizole Tablet
Take Entamizole Tablet exactly as directed by your doctor. It is usually taken after meals with a full glass of water to reduce stomach upset. Complete the entire prescribed course, even if your symptoms improve before the medicine is finished. Stopping treatment too early may allow the infection to return.
Possible Side Effects
Like all medicines, Entamizole Tablet may cause side effects, although not everyone experiences them. Common side effects include:
- Nausea or vomiting
- Metallic taste in the mouth
- Abdominal discomfort
- Loss of appetite
- Headache
- Dizziness
Seek immediate medical attention if you develop severe allergic reactions, persistent numbness or tingling, seizures, or severe skin reactions.
Precautions
Before taking Entamizole Tablet, inform your doctor if you:
- Are pregnant or breastfeeding
- Have liver disease
- Have a history of neurological disorders
- Are allergic to metronidazole, diloxanide furoate, or similar medicines
Avoid drinking alcohol during treatment and for at least 48 hours after the last dose, as combining alcohol with metronidazole may cause flushing, nausea, vomiting, rapid heartbeat, and severe discomfort.
Drug Interactions
Entamizole Tablet may interact with medicines such as blood thinners (e.g., warfarin), lithium, phenytoin, phenobarbital, and certain other antibiotics. Always inform your healthcare provider about all medicines, supplements, and herbal products you are taking.
Are there any Alternatives to Entamizole?
Yes, there are quite a few alternatives to Entamizole tablet in Pakistan. If Entamizole Tablet is unavailable, the best alternative is another brand containing the same active ingredients:
Metronidazole + Diloxanide Furoate
Several brands with this combination are available in Pakistan, although availability varies by pharmacy. Examples include:
- Metodine DF
- Dizole
- Entametox
- Diloxazole
- Zolt DS
- Diloxamet DS
Important note: Do not switch from Entamizole to another medicine without consulting a healthcare professional.
Disclaimer
This information is intended for educational purposes only and should not replace professional medical advice. Always use Entamizole Tablet exactly as prescribed by your doctor. If your symptoms persist, worsen, or you experience severe side effects, seek medical attention promptly.




