Angised 0.5 mg Tablet

Angised Tablet is a fast-acting medicine containing Glyceryl Trinitrate (GTN) 0.5 mg, also known as nitroglycerin. It belongs to a group of medicines called organic nitrates and is primarily used for the rapid relief and prevention of angina (heart-related chest pain). In Pakistan, Angised 0.5 mg is marketed by GSK Pakistan.

Angina occurs when the heart muscle does not receive enough oxygen-rich blood, often because the coronary arteries have become narrowed. Angised relaxes and widens blood vessels, reducing the workload on the heart and helping improve the balance between the heart’s oxygen supply and demand.

What Is Angised Tablet Used For?

The primary uses of Angised include:

• Rapid relief of angina attacks
• Prevention of angina before activities known to trigger chest pain
• Heart-related chest pain due to coronary artery disease
• Reduction of the workload on the heart

Angised should be used according to a doctor’s instructions, particularly because chest pain can sometimes indicate a heart attack or another medical emergency.

How Does Angised Work?

Glyceryl trinitrate is a vasodilator, meaning that it relaxes and widens blood vessels.

Its effects on the veins reduce the amount of blood returning to the heart, thereby reducing the workload and oxygen requirements of the heart muscle. It can also improve coronary blood flow.

Because Angised 0.5 mg is designed for sublingual administration, its effect can begin rapidly, making it useful for acute angina symptoms.

How to Take Angised 0.5 mg

Angised 0.5 mg is intended to be taken under the tongue (sublingually).

When prescribed for an angina attack:

• Sit down before taking the medicine because dizziness or a fall in blood pressure can occur.
• Place the prescribed tablet under the tongue.
• Allow it to dissolve rather than routinely swallowing it like an ordinary tablet.
• Follow the repeat-dose instructions given by your doctor.
• Do not exceed the prescribed amount.

It may also be prescribed before physical activity or another situation that predictably causes angina.

Because instructions for acute chest pain are safety-critical, patients should have an individualized action plan from their doctor about when to use GTN and when to seek emergency medical assistance.

Angised and Chest Pain: An Important Warning

Angised may relieve angina, but new, severe, unusual, or persistent chest pain should never simply be assumed to be ordinary angina.

Seek emergency medical attention if chest pain is severe, does not improve according to your prescribed GTN action plan, or is accompanied by symptoms such as:

• Shortness of breath
• Cold sweating
• Nausea or vomiting
• Fainting or severe weakness
• Pain spreading to the arm, shoulder, back, neck, or jaw

These symptoms can occur during a heart attack and require urgent medical assessment.

Common Side Effects

Because glyceryl trinitrate widens blood vessels, possible side effects include:

• Headache
• Dizziness
• Lightheadedness
• Flushing
• Low blood pressure
• Weakness
• Increased heart rate
• Fainting, particularly if blood pressure falls significantly

Headache is particularly common with nitrate medicines and results from their blood-vessel-widening effect.

Patients should sit or lie down if they become significantly dizzy after taking Angised.

Angised and Erectile Dysfunction Medicines

One of the most important safety considerations with Angised is its interaction with PDE-5 inhibitors used for erectile dysfunction, including medicines such as sildenafil, tadalafil and vardenafil.

Combining these medicines with nitrates can cause a dangerous fall in blood pressure.

Patients prescribed Angised should make sure their doctor knows about all medicines they use, including medicines for erectile dysfunction and pulmonary hypertension.

Other Precautions

Tell your doctor if you have:

• Very low blood pressure
• Severe anemia
• Certain heart valve or structural heart conditions
• Recent head injury or cerebral hemorrhage
• Significant liver or kidney disease
• Other cardiovascular conditions

Alcohol can further lower blood pressure and increase dizziness associated with nitrate treatment.

How Should Angised Be Stored?

Sublingual glyceryl trinitrate can lose effectiveness when improperly stored. Keep Angised in its original packaging/container, protected from excessive heat, light, and moisture, and follow the storage instructions supplied with the medicine.

Check the expiry date regularly, particularly if you carry Angised for emergency use.

Frequently Asked Questions

What is Angised Tablet used for?

Angised 0.5 mg is primarily used for the rapid relief and prevention of angina, a type of chest pain caused by inadequate oxygen supply to the heart muscle.

What does Angised contain?

Each Angised Tablet contains Glyceryl Trinitrate BP 0.5 mg.

Is Angised a blood pressure medicine?

Its active ingredient lowers blood pressure by widening blood vessels, but Angised 0.5 mg sublingual tablets are primarily used for angina relief and prevention, rather than routine treatment of hypertension.

Should Angised be swallowed?

Angised 0.5 mg for acute angina is designed for sublingual use, meaning the tablet is placed under the tongue and allowed to dissolve.

Why does Angised cause headaches?

Glyceryl trinitrate widens blood vessels. This vasodilating effect can produce headaches, particularly when treatment is first used.

Can Angised be taken with Viagra or sildenafil?

Nitrates such as glyceryl trinitrate should not be combined with PDE-5 inhibitors such as sildenafil because the combination can cause dangerously low blood pressure. Patients should discuss the required separation period with their doctor because it differs between PDE-5 medicines.

Disclaimer: This information is for educational purposes only and does not replace professional medical advice or emergency care. Angised is used for heart-related chest pain and should be taken according to a healthcare professional’s instructions. New, severe, worsening, or persistent chest pain requires urgent medical assessment.