Sibelium 5 mg Capsule is a prescription medicine containing flunarizine hydrochloride. It is mainly used for the prevention of migraine and may also be prescribed for certain forms of vertigo (dizziness associated with balance-system disorders).
In Pakistan, Sibelium 5 mg is manufactured by Aspin Pharma (Pvt.) Ltd. and is available as an oral capsule. Aspin’s current product information lists each capsule as containing flunarizine hydrochloride 5 mg.
What Is Sibelium Used For?
Sibelium is most commonly prescribed to people who experience recurrent migraine attacks.
Its purpose is to reduce the frequency or severity of future migraine episodes rather than simply providing immediate pain relief when a headache has already started.
Doctors may prescribe Sibelium for:
- Migraine prevention
- Recurrent migraine headaches
- Migraine with or without aura, when preventive treatment is appropriate
- Vertigo associated with certain vestibular disorders
The official Pakistani product page identifies migraine and vertigo among its indications.
Sibelium for Migraine Prevention
People who experience frequent or disabling migraines may be offered a preventive medicine in addition to medication used during individual attacks.
Flunarizine is one such preventive option.
When effective, regular treatment may help:
- Reduce how frequently migraines occur
- Reduce the severity of attacks
- Improve migraine control over time
The benefit is not necessarily immediate. Preventive migraine treatment usually needs to be assessed over time to determine whether it is providing a meaningful reduction in attacks.
Sibelium does not work like a painkiller
Sibelium should not be confused with medicines such as paracetamol, NSAIDs or migraine-specific medicines used to manage an acute migraine attack.
Its main role is prevention.
How Does Sibelium Work?
Flunarizine is a selective calcium-entry blocker with effects on the nervous and vestibular systems.
Its pharmacological actions can help stabilize cellular responses involved in migraine and certain balance disorders. This is why flunarizine is used as a preventive treatment rather than simply as an analgesic.
Sibelium for Vertigo
Sibelium may also be prescribed for vertigo of vestibular origin in appropriately selected patients.
Vertigo is the sensation that you or your surroundings are moving or spinning when no such movement is occurring. It can arise from several different conditions, so persistent or recurrent vertigo should be properly assessed rather than automatically treated with Sibelium.
The appropriate treatment depends on the underlying cause.
How to Take Sibelium
Take Sibelium exactly as prescribed by your doctor.
Because sleepiness and sedation can occur, flunarizine is commonly administered in the evening. The exact dose and treatment schedule, however, depend on factors such as age, response to treatment and adverse effects.
Important points include:
- Swallow the capsule with water.
- Take it according to the prescribed schedule.
- Do not increase the dose yourself.
- Do not continue it indefinitely without medical review.
- If you miss a dose, do not double the next dose unless specifically instructed.
Treatment should be reviewed periodically to determine whether it remains necessary and effective.
Common Side Effects of Sibelium
Sibelium can cause side effects, although not everyone experiences them.
Important commonly reported effects include:
- Drowsiness or sleepiness
- Fatigue
- Increased appetite
- Weight gain
- Nausea or digestive discomfort
Drowsiness is particularly important when treatment is first started.
Movement-Related Side Effects
Flunarizine can occasionally cause extrapyramidal symptoms, particularly during longer treatment or in susceptible individuals.
These can resemble features seen in Parkinson’s disease and may include:
- Tremor
- Muscle stiffness
- Slowness of movement
- Restlessness
- Abnormal involuntary movements
This is an important reason why Sibelium should not be treated as a harmless long-term dizziness medicine.
A patient who develops new tremor, stiffness or unusual movements while taking Sibelium should contact their doctor.
Who Should Not Take Sibelium?
Sibelium may be unsuitable for people with certain medical histories.
Particular caution is required in people with:
- Current or recurrent depression
- Parkinson’s disease
- Previous extrapyramidal or movement disorders
- Allergy to flunarizine or another component of the capsule
Your doctor should know about your neurological and psychiatric history before prescribing flunarizine.
How Long Is Sibelium Taken for Migraine?
Migraine prevention is usually assessed over a period of time rather than after one or two doses.
Your doctor may evaluate:
- Number of migraine days
- Frequency of attacks
- Severity of migraines
- Need for acute migraine medicines
- Side effects
- Overall improvement in daily activities
If there is no worthwhile improvement after an adequate trial, the doctor may reconsider treatment.
Long-term therapy should also be reviewed periodically because of adverse effects such as weight gain, depression and movement disorders.
Keeping a migraine diary can make this assessment easier.
When to Contact Your Doctor
Seek medical advice if you develop:
- New or worsening depression
- Tremor
- Muscle stiffness
- Slowed movements
- Significant involuntary movements
- Excessive or persistent drowsiness
- Significant unexplained weight gain
- Symptoms of a serious allergic reaction
These symptoms are particularly important during prolonged treatment.
Important Safety Information
Sibelium is a preventive neurological medicine, not an ordinary headache capsule. Its potential to cause drowsiness, weight gain, depression and movement-related adverse effects makes appropriate patient selection and medical follow-up important.
People experiencing a new, sudden or unusually severe headache, weakness on one side, difficulty speaking, loss of consciousness, seizures, fever with neck stiffness, or significant changes in vision should seek urgent medical assessment rather than assuming the symptoms are migraine.




