Migril Tablet

Migril Tablet is a combination medicine used for the relief of acute migraine attacks. In Pakistan, Migril contains three active ingredients: ergotamine tartrate 2 mg, cyclizine hydrochloride 50 mg, and caffeine hydrate 100 mg. GSK Pakistan currently lists this formulation in its product portfolio.

The three ingredients have different roles in managing a migraine attack. Ergotamine acts on blood vessels involved in migraine, cyclizine helps control associated nausea and vomiting, while caffeine contributes to the overall anti-migraine effect.

Composition

Each Migril tablet contains:

• Ergotamine Tartrate: 2 mg
• Cyclizine Hydrochloride: 50 mg
• Caffeine Hydrate: 100 mg

Uses of Migril Tablet

Migril is primarily used for the relief of an acute migraine attack.

Migraine may cause symptoms including:

• Moderate to severe headache
• Throbbing or pulsating pain
• Nausea or vomiting
• Sensitivity to light
• Sensitivity to sound

Migril is intended for treating migraine attacks rather than being used as a routine everyday painkiller.

How Does Migril Work?

Migril combines three medicines.

Ergotamine has vasoconstrictive effects and is used to help relieve an acute migraine attack.

Cyclizine is an antihistamine with antiemetic properties that can help reduce nausea and vomiting associated with migraine.

Caffeine contributes to the anti-migraine action of the combination.

How to Take Migril

Migril should be taken according to the instructions of your doctor or pharmacist and the approved product information.

Because the medicine contains ergotamine, the recommended maximum amount should not be exceeded. Excessive or frequent ergotamine use can cause potentially serious adverse effects.

People experiencing frequent migraines should consult a healthcare professional rather than repeatedly self-treating attacks with Migril.

Possible Side Effects

Migril may cause side effects such as:

• Nausea
• Vomiting
• Dizziness
• Drowsiness
• Dry mouth
• Abdominal discomfort
• Weakness
• Muscle cramps

Cyclizine can cause drowsiness or reduced alertness in some people. Avoid driving or operating machinery if the medicine affects your ability to do so.

Important Precautions

Migril is not suitable for everyone. Extra caution is necessary because ergotamine constricts blood vessels.

Tell your healthcare professional about your medical conditions and all medicines you are taking before using Migril.

Particular care is required in people with cardiovascular or circulation problems, liver or kidney disease, and those taking medicines that may interact with ergotamine.

Migril During Pregnancy

Medicines containing ergotamine should not be used during pregnancy because ergotamine can affect uterine and vascular function.

If you are pregnant, planning a pregnancy, or breastfeeding, speak with a healthcare professional before taking migraine medicines.

Migril and Other Migraine Medicines

Migril should not automatically be combined with other migraine treatments.

Some medicines, including triptans and certain other drugs that affect blood vessels or ergotamine metabolism, can interact significantly with ergotamine.

Always tell your doctor or pharmacist which migraine medicines and other medications you are currently taking.

When Should You See a Doctor for Migraine?

Consult a healthcare professional if headaches are frequent, becoming more severe, changing in pattern, interfering significantly with daily activities, or requiring increasingly frequent medication.

A sudden extremely severe headache or headache accompanied by neurological symptoms such as weakness, difficulty speaking, confusion, seizures, or loss of consciousness requires urgent medical assessment.

Medical Disclaimer

This information is provided for general educational purposes and does not replace professional medical advice, diagnosis, or treatment. Migril contains ergotamine and should be used according to appropriate professional guidance and the product information.